OTA, Tsuguhito: search on Z-Library

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1

Empagliflozin reverses obesity and insulin resistance through fat browning and alternative macrophage activation in mice fed a high-fat diet

Xu, Liang, Nagata, Naoto, Chen, Guanliang, Nagashimada, Mayumi, Zhuge, Fen, Ni, Yinhua, Sakai, Yuriko, Kaneko, Shuichi, Ota, Tsuguhito

Journal:

BMJ Open Diabetes Research & Care

Year:

2019

File:

PDF, 7.31 MB

2019

2

Regulation of Gut Microbiota and Metabolic Endotoxemia with Dietary Factors

Fuke, Nobuo, Nagata, Naoto, Suganuma, Hiroyuki, Ota, Tsuguhito

Journal:

Year:

2019

Language:

english

File:

PDF, 940 KB

english, 2019

3

Intake of Ï-6 Polyunsaturated Fatty Acid-Rich Vegetable Oils and Risk of Lifestyle Diseases

Yamashima, Tetsumori, Ota, Tsuguhito, Mizukoshi, Eishiro, Nakamura, Hiroyuki, Yamamoto, Yasuhiko, Kikuchi, Mitsuru, Yamashita, Tatsuya, Kaneko, Shuichi

Journal:

Advances in Nutrition: An International Review Journal

Year:

2020

File:

PDF, 6.61 MB

2020

4

391 - Circulating Extracellular Vesicle Encapsulated Long Noncoding RNA HULC would be a Potential Biomarker for Human Pancreatic Cancer

Takahashi, Kenji, Ota, Yu, Iwamoto, Hidetaka, Yamakita, Keisuke, Kitano, Yohei, Makino, Yuichi, Ota, Tsuguhito

Journal:

Gastroenterology

Year:

2018

Language:

english

File:

PDF, 754 KB

english, 2018

5

Hypoxia-inducible factor-1α is the therapeutic target of the SGLT2 inhibitor for diabetic nephropathy

Bessho, Ryoichi, Takiyama, Yumi, Takiyama, Takao, Kitsunai, Hiroya, Takeda, Yasutaka, Sakagami, Hidemitsu, Ota, Tsuguhito

Journal:

Scientific Reports

Year:

2019

Language:

english

File:

PDF, 1.80 MB

english, 2019

6

Obesity Upregulates Genes Involved in Oxidative Phosphorylation in Livers of Diabetic Patients

Toshinari Takamura, Hirofumi Misu, Naoto Matsuzawa-Nagata, Masaru Sakurai, Tsuguhito Ota, Akiko Shimizu, Seiichiro Kurita, Yumie Takeshita, Hitoshi Ando, Masao Honda, Shuichi Kaneko

Journal:

Year:

2008

Language:

english

File:

PDF, 1.04 MB

english, 2008

7

SGLT2 Inhibition by Empagliflozin Promotes Fat Utilization and Browning and Attenuates Inflammation and Insulin Resistance by Polarizing M2 Macrophages in Diet-induced Obese Mice

Xu, Liang, Nagata, Naoto, Nagashimada, Mayumi, Zhuge, Fen, Ni, Yinhua, Chen, Guanliang, Mayoux, Eric, Kaneko, Shuichi, Ota, Tsuguhito

Journal:

Year:

2017

Language:

english

File:

PDF, 5.16 MB

english, 2017

8

Mo1391 – Circulating Extracellular Vesicle Lncrna Linc02280 is a Novel Biomarker for Human Pancreatic Ductal Adenocarcinoma

Takahashi, Kenji, Ota, Yu, Suzuki, Yuko, Iwamoto, Hidetaka, Yamakita, Keisuke, Kitano, Yohei, Ota, Tsuguhito

Journal:

Gastroenterology

Year:

2019

Language:

english

File:

PDF, 571 KB

english, 2019

9

Effect of pioglitazone on muscle sympathetic nerve activity in type 2 diabetes mellitus with alpha-glucosidase inhibitor

Daisuke Kobayashi, Masayuki Takamura, Hisayoshi Murai, Soichiro Usui, Tatsunori Ikeda, Jun-ichiro Inomata, Shin-ichiro Takashima, Takeshi Kato, Hiroshi Furusho, Yumie Takeshita, Tsuguhito Ota, Toshina

Journal:

Autonomic Neuroscience

Year:

2010

Language:

english

File:

PDF, 429 KB

english, 2010

10

Measurement of Thyroid Blood Flow Area Is Useful for Diagnosing the Cause of Thyrotoxicosis

Kurita, Seiichiro, Sakurai, Masaru, Kita, Yuki, Ota, Tsuguhito, Ando, Hitoshi, Kaneko, Shuichi, Takamura, Toshinari

Journal:

Year:

2005

Language:

english

File:

PDF, 84 KB

english, 2005

11

Prevention and Reversal of Lipotoxicity-Induced Hepatic Insulin Resistance and Steatohepatitis in Mice by an Antioxidant Carotenoid, β-Cryptoxanthin

Ni, Yinhua, Nagashimada, Mayumi, Zhan, Lili, Nagata, Naoto, Kobori, Masuko, Sugiura, Minoru, Ogawa, Kazunori, Kaneko, Shuichi, Ota, Tsuguhito

Journal:

Year:

2015

Language:

english

File:

PDF, 2.47 MB

english, 2015

12

Tumor necrosis factor-α–induced production of plasminogen activator inhibitor 1 and its regulation by pioglitazone and cerivastatin in a nonmalignant human hepatocyte cell line

Yumie Takeshita, Toshinari Takamura, Erika Hamaguchi, Akiko Shimizu, Tsuguhito Ota, Masaru Sakurai, Shuichi Kaneko

Journal:

Year:

2006

Language:

english

File:

PDF, 259 KB

english, 2006

13

Hepatic Transcriptome Profiles of Mice with Diet-Induced Nonalcoholic Steatohepatitis Treated with Astaxanthin and Vitamin E

Kobori, Masuko, Takahashi, Yumiko, Sakurai, Mutsumi, Ni, Yinhua, Chen, Guanliang, Nagashimada, Mayumi, Kaneko, Shuichi, Ota, Tsuguhito

Journal:

International Journal of Molecular Sciences

Year:

2017

Language:

english

File:

PDF, 2.70 MB

english, 2017

14

Obesity-Induced Inflammation and Insulin Resistance

Journal:

Frontiers in Endocrinology

Year:

2014

Language:

english

File:

PDF, 373 KB

english, 2014

15

Comparison of acarbose versus voglibose monotherapy on GLP-1 secretion and postprandial dyslipidemia in patients with type 2 diabetes

Shima, Kosuke, Usuda, Rika, Ni, Yinhua, Kaneko, Shuichi, Takamura, Toshinari, Ota, Tsuguhito

Journal:

Diabetes Research and Clinical Practice

Year:

2016

Language:

english

File:

PDF, 51 KB

english, 2016

16

β-Cryptoxanthin Alleviates Diet-Induced Nonalcoholic Steatohepatitis by Suppressing Inflammatory Gene Expression in Mice

Kobori, Masuko, Ni, Yinhua, Takahashi, Yumiko, Watanabe, Natsumi, Sugiura, Minoru, Ogawa, Kazunori, Nagashimada, Mayumi, Kaneko, Shuichi, Naito, Shigehiro, Ota, Tsuguhito, Aguila, Marcia B.

Journal:

Year:

2014

Language:

english

File:

PDF, 2.50 MB

english, 2014

17

Role of vitamin E in nonalcoholic fatty liver disease

Nagashimada, Mayumi, Ota, Tsuguhito

Journal:

Year:

2018

Language:

english

File:

PDF, 839 KB

english, 2018

18

Lipid-induced oxidative stress causes steatohepatitis in mice fed an atherogenic diet

Naoto Matsuzawa, Toshinari Takamura, Seiichiro Kurita, Hirofumi Misu, Tsuguhito Ota, Hitoshi Ando, Masayoshi Yokoyama, Masao Honda, Yoh Zen, Yasuni Nakanuma, Ken-ichi Miyamoto, Shuichi Kaneko

Journal:

Year:

2007

Language:

english

File:

PDF, 1.75 MB

english, 2007

19

Reply to the Letter to the Editor by Li et al.: Bioinformatics Analysis in Mice with Diet-Induced Nonalcoholic Steatohepatitis Treated with Astaxanthin and Vitamin E

Kobori, Masuko, Takahashi, Yumiko, Sakurai, Mutsumi, Ni, Yinhua, Chen, Guanliang, Nagashimada, Mayumi, Kaneko, Shuichi, Ota, Tsuguhito

Journal:

International Journal of Molecular Sciences

Year:

2017

Language:

english

File:

PDF, 128 KB

english, 2017

20

Pirfenidone prevents and reverses hepatic insulin resistance and steatohepatitis by polarizing M2 macrophages

Chen, Guanliang, Ni, Yinhua, Nagata, Naoto, Xu, Liang, Zhuge, Fen, Nagashimada, Mayumi, Kaneko, Shuichi, Ota, Tsuguhito

Journal:

Laboratory Investigation

Year:

2019

Language:

english

File:

PDF, 3.97 MB

english, 2019

21

Fulminating Onset Type 1 Diabetes with Positivity for Anti-GAD Antibody and Elevated Pancreatic Exocrine Enzyme Concentrations

KAHARA, Toshio, TAKAMURA, Toshinari, ANDO, Hitoshi, SAKURAI, Masara, OTA, Tsuguhito, MlSAKI, Tsuguho, OBA, Sakae, IGUCHI, Masahara, KOMORI, Kazutoshi, KOBAYASHI, Ken-ichi

Journal:

Internal Medicine

Year:

2003

Language:

english

File:

PDF, 692 KB

english, 2003

22

The effects of ezetimibe on non-alcoholic fatty liver disease and glucose metabolism: a randomised controlled trial

Takeshita, Yumie, Takamura, Toshinari, Honda, Masao, Kita, Yuki, Zen, Yoh, Kato, Ken-ichiro, Misu, Hirofumi, Ota, Tsuguhito, Nakamura, Mikiko, Yamada, Kazutoshi, Sunagozaka, Hajime, Arai, Kuniaki, Yam

Journal:

Year:

2014

Language:

english

File:

PDF, 276 KB

english, 2014

23

Astaxanthin prevents and reverses diet-induced insulin resistance and steatohepatitis in mice: A comparison with vitamin E

Ni, Yinhua, Nagashimada, Mayumi, Zhuge, Fen, Zhan, Lili, Nagata, Naoto, Tsutsui, Akemi, Nakanuma, Yasuni, Kaneko, Shuichi, Ota, Tsuguhito

Journal:

Scientific Reports

Year:

2015

Language:

english

File:

PDF, 3.11 MB

english, 2015

24

Increment of plasma glucose by exogenous glucagon is associated with present and future renal function in type 2 diabetes:a retrospective study from glucagon stimulation test

Takeda, Yasutaka, Fujita, Yukihiro, Bessho, Ryoichi, Sato, Mao, Abe, Tomoe, Yanagimachi, Tsuyoshi, Sakagami, Hidemitsu, Abiko, Atsuko, Takiyama, Yumi, Ota, Tsuguhito, Haneda, Masakazu

Journal:

BMC Endocrine Disorders

Year:

2019

File:

PDF, 614 KB

2019

25

Adipose Tissue Macrophage Phenotypes and Characteristics: The Key to Insulin Resistance in Obesity and Metabolic Disorders

Ni, Yinhua, Ni, Liyang, Zhuge, Fen, Xu, Liang, Fu, Zhengwei, Ota, Tsuguhito

Journal:

Year:

2020

File:

PDF, 720 KB

2020

26

Olmesartan ameliorates a dietary rat model of non-alcoholic steatohepatitis through its pleiotropic effects

Seiichiro Kurita, Toshinari Takamura, Tsuguhito Ota, Naoto Matsuzawa-Nagata, Yuki Kita, Masafumi Uno, Satoko Nabemoto, Kazuhide Ishikura, Hirofumi Misu, Hitoshi Ando, Yoh Zen, Yasuni Nakanuma, Shuichi

Journal:

European Journal of Pharmacology

Year:

2008

Language:

english

File:

PDF, 1.43 MB

english, 2008

27

Inverse Correlation between Serum Levels of Selenoprotein P and Adiponectin in Patients with Type 2 Diabetes

Misu, Hirofumi, Ishikura, Kazuhide, Kurita, Seiichiro, Takeshita, Yumie, Ota, Tsuguhito, Saito, Yoshiro, Takahashi, Kazuhiko, Kaneko, Shuichi, Takamura, Toshinari, Luque, Raul M.

Journal:

Year:

2012

Language:

english

File:

PDF, 239 KB

english, 2012

28

Tranilast, an antifibrogenic agent, ameliorates a dietary rat model of nonalcoholic steatohepatitis

Masafumi Uno, Seiichiro Kurita, Hirofumi Misu, Hitoshi Ando, Tsuguhito Ota, Naoto Matsuzawa-Nagata, Yuki Kita, Satoko Nabemoto, Hiroshi Akahori, Yoh Zen, Yasuni Nakanuma, Shuichi Kaneko, Toshinari Tak

Journal:

Year:

2008

Language:

english

File:

PDF, 2.65 MB

english, 2008

29

Immune regulation of glucose and lipid metabolism

Journal:

Diabetology International

Year:

2017

Language:

english

File:

PDF, 1.92 MB

english, 2017

30

Liver steatosis, but not fibrosis, is associated with insulin resistance in nonalcoholic fatty liver disease

Masaru Sakurai, Toshinari Takamura, Tsuguhito Ota, Hitoshi Ando, Hiroshi Akahori, Kyosuke Kaji, Motoko Sasaki, Yasuni Nakanuma, Katsuyuki Miura, Shuichi Kaneko

Journal:

Journal of Gastroenterology

Year:

2007

Language:

english

File:

PDF, 142 KB

english, 2007

31

Metformin Prevents and Reverses Inflammation in a Non-Diabetic Mouse Model of Nonalcoholic Steatohepatitis

Kita, Yuki, Takamura, Toshinari, Misu, Hirofumi, Ota, Tsuguhito, Kurita, Seiichiro, Takeshita, Yumie, Uno, Masafumi, Matsuzawa-Nagata, Naoto, Kato, Ken-ichiro, Ando, Hitoshi, Fujimura, Akio, Hayashi,

Journal:

Year:

2012

Language:

english

File:

PDF, 3.37 MB

english, 2012

32

Roles of Chemokines and Chemokine Receptors in Obesity-Associated Insulin Resistance and Nonalcoholic Fatty Liver Disease

Xu, Liang, Kitade, Hironori, Ni, Yinhua, Ota, Tsuguhito

Journal:

Year:

2015

Language:

english

File:

PDF, 1.36 MB

english, 2015

33

DPP-4 inhibition with anagliptin reduces lipotoxicity-induced insulin resistance and steatohepatitis in male mice

Sakai, Yuriko, Chen, Guanliang, Ni, Yinhua, Zhuge, Fen, Xu, Liang, Nagata, Naoto, Kaneko, Shuichi, Ota, Tsuguhito, Nagashimada, Mayumi

Journal:

Year:

2020

File:

PDF, 2.05 MB

2020

34

Micronutrient Antioxidants and Nonalcoholic Fatty Liver Disease

Chen, Guanliang, Ni, Yinhua, Nagata, Naoto, Xu, Liang, Ota, Tsuguhito

Journal:

International Journal of Molecular Sciences

Year:

2016

Language:

english

File:

PDF, 928 KB

english, 2016

35

Glucoraphanin: A broccoli sprout extract that ameliorates obesity-induced inflammation and insulin resistance

Xu, Liang, Nagata, Naoto, Ota, Tsuguhito

Journal:

Year:

2018

Language:

english

File:

PDF, 1.74 MB

english, 2018

36

Empagliflozin reverses obesity and insulin resistance through fat browning and alternative macrophage activation in mice fed a high-fat diet

Xu, Liang, Nagata, Naoto, Chen, Guanliang, Nagashimada, Mayumi, Zhuge, Fen, Ni, Yinhua, Sakai, Yuriko, Kaneko, Shuichi, Ota, Tsuguhito

Journal:

BMJ Open Diabetes Research & Care

Year:

2019

Language:

english

File:

PDF, 7.31 MB

english, 2019

37

Gender Differences in the Association between Anthropometric Indices of Obesity and Blood Pressure in Japanese

SAKURAI, Masaru, MIURA, Katsuyuki, TAKAMURA, Toshinari, OTA, Tsuguhito, ISHIZAKI, Masao, MORIKAWA, Yuko, KIDO, Teruhiko, NARUSE, Yuchi, NAKAGAWA, Hideaki

Journal:

Hypertension Research

Year:

2006

Language:

english

File:

PDF, 78 KB

english, 2006

38

Insulin Resistance Accelerates a Dietary Rat Model of Nonalcoholic Steatohepatitis

Tsuguhito Ota, Toshinari Takamura, Seiichiro Kurita, Naoto Matsuzawa, Yuki Kita, Masafumi Uno, Hiroshi Akahori, Hirofumi Misu, Masaru Sakurai, Yoh Zen, Yasuni Nakanuma, Shuichi Kaneko

Journal:

Gastroenterology

Year:

2007

Language:

english

File:

PDF, 1.95 MB

english, 2007

39

Novel Action of Carotenoids on Non-Alcoholic Fatty Liver Disease: Macrophage Polarization and Liver Homeostasis

Ni, Yinhua, Zhuge, Fen, Nagashimada, Mayumi, Ota, Tsuguhito

Journal:

Year:

2016

Language:

english

File:

PDF, 1.88 MB

english, 2016

40

A Liver-Derived Secretory Protein, Selenoprotein P, Causes Insulin Resistance

Hirofumi Misu, Toshinari Takamura, Hiroaki Takayama, Hiroto Hayashi, Naoto Matsuzawa-Nagata, Seiichiro Kurita, Kazuhide Ishikura, Hitoshi Ando, Yumie Takeshita, Tsuguhito Ota, Masaru Sakurai, Tatsuya

Journal:

Cell Metabolism

Year:

2010

Language:

english

File:

PDF, 785 KB

english, 2010

41

Factors associated with improvement of fasting plasma glucose level by mealtime dosing of a rapid-acting insulin analog in type 2 diabetes

Toshinari Takamura, Masaru Sakurai, Masumi Nakamura, Akiko Shimizu, Tsuguhito Ota, Hirofumi Misu, Yumie Takeshita, Naomi Tsuchiyama, Seiichiro Kurita, Hitoshi Ando, Shuichi Kaneko

Journal:

Diabetes Research and Clinical Practice

Year:

2007

Language:

english

File:

PDF, 163 KB

english, 2007

42

Fatty liver as a consequence and cause of insulin resistance: Lessons from type 2 diabetic liver

Takamura, Toshinari, Misu, Hirofumi, Ota, Tsuguhito, Kaneko, Shuichi

Journal:

Endocrine Journal

Year:

2012

Language:

english

File:

PDF, 2.83 MB

english, 2012

43

Astaxanthin prevents and reverses insulin resistance and steatohepatitis: A comparison with vitamin E

Xu, Liang, Ni, Yinhua, Nagashimada, Mayumi, Zhuge, Fen, Nagata, Naoto, Kaneko, Shuichi, Ota, Tsuguhito

Journal:

Diabetes Research and Clinical Practice

Year:

2016

Language:

english

File:

PDF, 37 KB

english, 2016

44

BETA-CRYPTOXANTHIN EXERTS BETTER CARDIOPROTECTION AGAINST CARDIAC ISCHEMIA-REPERFUSION INJURY THAN ASTAXANTHIN VIA PROTECTING MITOCHONDRIAL DYSFUNCTION IN MICE

Pongkan, Wanpitak, Xu, Liang, Takatori, Osamu, Nagata, Naoto, Ni, Yinhua, Nakayama, Mai, Chattipakorn, Siriporn, Usui, Soichiro, Ota, Tsuguhito, Chattipakorn, Nipon

Journal:

Journal of the American College of Cardiology

Year:

2017

Language:

english

File:

PDF, 890 KB

english, 2017

45

Chemokine Systems Link Obesity to Insulin Resistance

Journal:

Diabetes & Metabolism Journal

Year:

2013

Language:

english

File:

PDF, 561 KB

english, 2013

46

Significance of IA-2 antibody in Japanese type 1 diabetes: its association with GAD antibody

Tsuguhito Ota, Toshinari Takamura, Yukihiro Nagai, Yukihiro Bando, Rika Usuda

Journal:

Diabetes Research and Clinical Practice

Year:

2005

Language:

english

File:

PDF, 88 KB

english, 2005

47

Nonalcoholic Fatty Liver Disease and Insulin Resistance: New Insights and Potential New Treatments

Kitade, Hironori, Chen, Guanliang, Ni, Yinhua, Ota, Tsuguhito

Journal:

Year:

2017

Language:

english

File:

PDF, 1.44 MB

english, 2017

48

723 Differential gene expression in the liver of type 2 diabetic patients: features of atherosclerosis and NASH

Toshinari Takamura, Masao Honda, Masaru Sakurai, Tsuguhito Ota, Shuichi Kaneko

Journal:

Year:

2003

Language:

english

File:

PDF, 146 KB

english, 2003

49

Selenoprotein P as a diabetes-associated hepatokine that impairs angiogenesis by inducing VEGF resistance in vascular endothelial cells

Ishikura, Kazuhide, Misu, Hirofumi, Kumazaki, Masafumi, Takayama, Hiroaki, Matsuzawa-Nagata, Naoto, Tajima, Natsumi, Chikamoto, Keita, Lan, Fei, Ando, Hitoshi, Ota, Tsuguhito, Sakurai, Masaru, Takeshi

Journal:

Year:

2014

Language:

english

File:

PDF, 703 KB

english, 2014

50

CCR5

Journal:

Year:

2013

Language:

english

File:

PDF, 591 KB

english, 2013

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